Fertility TREATMENTS

King's Fertility Services Treatments

It can be real a life-changer when you know, or start to suspect, that your journey to parenthood will be more complex than expected. But there are many options in the field of fertility treatment, and we're here to help you pinpoint the treatment journey that will work for you – and your unique set of circumstances.

Whether you're a heterosexual couple, a same-sex couple or single, King's Fertility offers a full range of treatments. No matter who you are, our experienced team go to great lengths to ensure your time with us is as comfortable as possible. We work with you from the start to develop a personalised plan, and we stand with you on every step along the journey to life.

From your first fertility consultation, we will get to know you - your specific needs and requirements - and together we'll build a tailored treatment plan.

Female fertility Whatever your history, your expectations and your unique set of challenges, after your initial consultation with King's Fertility we will developing an appropriate treatment plan to maximise your chances of conception.

The King's Fertility team have decades of experience at the cutting edge of fertility, from providing patients with a female hormone profile, to embryo freezing and embryo transfer, care. We also work with the Fetal Medicine Foundation to ensure our work and our treatments are backed up by the most up-to-date breakthroughs, research and academic thinking.

IVF – in vitro fertilisation

Many still think that fertility starts and stops with IVF treatment, but even within the IVF process, there is no one-size-fits-all approach. For us, every woman’s physiology and family history are different and we look at all options to built a bespoke plan that fits.

Within the IVF family, there are variations on IVF including natural IVF, natural controlled IVF, and IVF-lite, all of which can involve fewer fertility drugs. We will determine the best course of action after we meet you and get to know your history and expectations.

Intracytoplasmic sperm injection (ICSI) and Physiological Intracytoplasmic sperm injection (PICSI) are options to aid IVF treatment, aiding fertilisation where there are additional challenges, such previously unsuccessful pregnancies or significant male factor problems.

Male Fertility

In men, where there are issues or suspected issues in fertility, a male fertility test or semen analysis can confirm the parameters of treatment, and determine the best course of action.

Advanced solutions such as surgical sperm retrieval and sperm washing are available at King's Fertility, but whatever the circumstances we will guide you through your options.

Using a sperm donor

If donor sperm is required, King's Fertility will help patients to choose appropriately while establishing the best course of treatment.

We also offer counselling to ensure would-be parents' psychological wellbeing is maintained throughout potentially challenging times.

How much does fertility treatment cost?

When you're considering fertility treatment, one of the natural questions that arises is what does it cost. Price is an issue which can quickly put the brakes on would-be parents' dreams of having a family.

For us, the decision to have a family shouldn't be based on parents' ability to pay more, so King’s Fertility offers personalised costs, which are laid out with full transparency from the very beginning of our relationship.

At consultation we agree on a treatment plan and all cost options are outlined from the beginning. We have taken this decision because the journey to life is emotional enough without an unforeseen financial burden when you're deep into the process.


 Services

+ Ovulation induction

If ovulation is not occurring, fertility drugs may help to stimulate normal follicle development and ovulation. The simplest treatment is a short course of fertility tablets taken at the onset of the period. Alternatively, hormone injections might be required. The response is monitored by ultrasound scans along with urine and blood tests.

Ovulation induction is then combined either with timed intercourse or alternatively with intrauterine insemination (IUI).

+ Intrauterine Insemination (IUI)

IUI is a when sperm is prepared in the lab and placed directly, using a fine catheter, into the uterus at the time of ovulation.

Natural IUI is when insemination takes place in a natural menstrual cycle. Stimulated IUI is when insemination is coupled with small doses of fertility drugs.

+ In vitro fertilisation (IVF)

Widely used in fertility, our IVF treatment protocols are personalised to suit individuals' needs and there is no “one-size-fits-all” approach. From daily hormone injections or tablets to ovulation-stopping medication, IVF involves several steps in the stimulation of egg growth and egg retrieval before an embryo is formed, incubated and transferred - and pregnancy is successful. IVF protocols can utilize a wide range of medication doses and types and we choose the one that fits you best.

Drug doses are personalised according to the desired response. Some stimulation protocols aim to optimise the number of eggs retrieved. Others, (for example “mini IVF” or “IVF-Lite”) start with low doses of medication to minimise the risk of overstimulation and aim at producing a lower number of eggs compared to higher stimulation doses but potentially of higher quality. Natural and natural controlled cycles are another form of IVF best suited for some women.

Natural IVF aims to collect the one single egg that grows naturally in every monthly cycle without the use of drugs. Natural controlled IVF uses a small amount of medication to follow the natural selection of this egg optimizing the treatment cycle. This particularly suits women that have low ovarian reserve, women who have had previous unsuccessful cycles with high doses of stimulation drugs, women with medical conditions contraindicating use of stimulation drugs or women who do not want to use many drugs for personal or religious reasons.

+ Complex/personalised stimulation protocols

At King’s Fertility we do not believe that there is one type or one form of IVF that works equally well for all. We believe in a physiological approach to IVF and choosing the right stimulation protocol for the right situation. Our treatment protocols are personalised to suit individuals' needs. We base our decisions on each woman’s own physiology and history to personalise the best treatment to them, being able to draw from the entire gamete of available protocols and when required devise entirely new bespoke ones.

+ Intracytoplasmic sperm injection (ICSI)

ICSI works in conjunction with IVF and enables fertilisation where there is a significant male factor problem.

Couples prepare for ICSI in the same way as for standard IVF, but the process is aided by identifying and injecting healthy sperm directly into the centre of each mature egg.

+ Physiological Intracytoplasmic sperm injection (PICSI)

PICSI is an improved sperm selection ICSI technique that may lead to better embryo quality and reduce the likelihood of miscarriage in certain cases. In PICSI, the sperm are selected based on their appearance, morphology and maturity. A specialised dish, the PICSI dish, provides a functional test to assist the embryologist’s selection of sperm for injection. The test is based on the ability of sperm to bind to hyaluronan (HA) hydrogel thus mimicking the natural binding of mature sperm to oocytes. PICSI could be considered if you have:

  • Undergone previous unsuccessful IVF or ICSI with poor embryo development
  • Had miscarriages with no cause identified
  • Sperm count of 1 million or greater

+ Time-lapse imaging (EmbryoScope)

EmbryoScope is a time-lapse system that allows embryologists to monitor your developing embryos throughout their development.

Images and information are analysed by computer software, ranking each embryo’s development potential to aid selection.

+ Extended blastocyst culture

In recent years, fertility experts have been able to extend the time the embryo is grown in the laboratory up to six days after egg collection, creating what are called blastocysts consisting of about 100 cells.

Only healthy embryos have the energy to turn into blastocysts, improving pregnancy outcomes and reducing multiple pregnancy rates after transfer.

+ Embryo glue

EmbryoGlue is a specially-designed solution that embryos can be cultured in prior to embryo transfer. It is suitable for all patients, but is particularly beneficial for those with good blastocyst quality but failed implantation in previous cycles. At King’s Fertility, it is used in both fresh and frozen embryo transfers. Prior to embryo transfer, the embryo can be coated in the EmbryoGlue. It is thought that the adhesive coating mimics the natural uterine hyaluran secretions and encourages the fusion of the embryo with the endometrium.

+ Endometrial scratching

An endometrial scratch is a procedure during which a fine catheter is placed in to the uterus timed to coincide with the middle of the second half of a woman’s cycle (called “mid-luteal”). The catheter is then used to cause a small amount of superficial injury to the lining of the womb. This will heal and regenerate with the next period. However, it has been proposed that this procedure might help embryos to implant when they are subsequently placed in to the uterus. It is mainly used for women who have experienced previous multiple unsuccessful IVF cycles, despite the transfer of good quality embryos.

+ Embryo freezing

After a cycle of IVF there are often surplus embryos that have not been transferred fresh but would otherwise be deemed as having a good chance of becoming a successful pregnancy. Sometimes, it is not appropriate for medical reasons to transfer an embryo fresh in the same cycle after an egg collection. And in some cases, electing to transfer embryos in a subsequent cycle and not in the same one as the egg collection was done in might offer a better chance of success. In these instances, embryos can be frozen and stored for later use. At King’s Fertility we employ the latest cryopreservation technics to ensure the best possible outcomes for you post freezing.

+ Frozen embryo transfer

If embryos, or eggs, have been previously frozen they can be thawed and replaced back in to a woman’s uterus to achieve a pregnancy. The timing of this is carefully monitored and planned, and it can be done both with and without the use of medication. This process is called a frozen embryo transfer (FET).

+ Donor egg treatment

For some women donor eggs may be required. This could be either because their own ovaries do not produce enough eggs, or their eggs are not of good enough quality to have a realistic chance of success. For others there may be a genetic or medical reason. Whatever the cause might be, King's Fertility will guide patients through the process, from choosing the appropriate donor programme, helping with selecting the appropriate donor eggs to establishing the appropriate treatment.

+ Donor sperm treatment

For single women or same sex couples, or for significant male fertility problems, donor sperm may be required. King's Fertility will guide patients through the process, from choosing the appropriate donor sperm to establishing the appropriate treatment.

+ Egg freezing

Social egg freezing is where a woman freezes her eggs for use in the future. General egg freezing mainly occurs for medical reasons, where a woman may be undergoing chemotherapy and would like to freeze her eggs prior to treatment.

To maximise the chances of conception following egg freezing, further stimulation cycles may be required.

+ Surrogacy

Some women cannot carry a pregnancy. This could be because they were born without a uterus (womb). Other times, women might have a medical condition which means that being pregnant would pose a significant risk to their health and life, and hence a pregnancy is therefore contraindicated. In these circumstances, surrogacy is an option. Although King's Fertility cannot provide women with a surrogate, once you have found one we will guide patients and surrogates alike through the steps and treatment. Surrogacy is a complex process and specialist legal advice is required.


Male fertility treatments

For more information please click the link below:

 TREATMENTS DUE for 2019

+ Assisted hatching

When embryos are transferred they must hatch out of the zona pellucida (embryo shell) so that the cells of the embryos can come into direct contact with the cells lining the womb.

To assist the hatching process, a laser makes a small hole in the shell of the embryo.

+ Preimplantation genetic screening (PGS)

Screening embryos for genetic abnormalities across all 24 chromosomes helps in selection and increases the chance of a healthy pregnancy. Chromosomally normal embryos have a higher chance of implantation and the resulting pregnancies have a lower chance of miscarriage.

+ Preimplantation genetic diagnosis (PGD)

PGD helps would-be parents to have a child at less risk of genetic or hereditary conditions.

From Thalassaemia, Sickle cell disease, Cystic fibrosis, Inheritable cancer pre-dispositions, Huntington’s Disease, Muscular dystrophies and Fragile-X, there is a full list of conditions currently licensed by the HFEA.